Often the synthesis of APIs for Oncology involves a large number of steps.
Normally the need for high containment is limited to the last steps, when the molecular structure becomes more similar to that of the API. Anyway the risk assessment for these intermediates is often incomplete. We prefer therefore to protect all the loading and discharge operations.
The chemical plant is multipurpose and includes a variety of reactors from 25L to 250L in glass, glass-lined and hastelloy.
Two of them can operate at low T (-70 °C).
Solids are isolated either by centrifuge or filter drier.
Max batch size currently 30 kg, with a filter dryer in hastelloy.